Publications

1.

Title: Magnetic Hyperthermia Properties of Iron Oxide Nanoparticles: The Effect of Concentration

Abstract: We investigated the effect of concentration on magnetic hyperthermia properties of Fe3O4 nanoparticles (NPs). The NPs were synthesized by co-precipitation method at 80 °C. Scanning electron microscope image showed that the mean diameter of NPs is about 18 nm. The XRD pattern indicated that the sample is pure Fe3O4 with spinel structure and the FT-IR spectroscopy confirmed formation of metal-oxygen bonds in the octahedral and tetrahedral spinel sub-lattice which further confirmed crystalline structure of the sample. The hyperthermia property of Fe3O4 NPs was investigated via an induction heater generating alternating magnetic field with frequency of 92 kHz. The temperature rise (DT) of suspension in the AC magnetic field was studied on different concentrations of NPs and the specific absorption rate (SAR) was obtained from Box-Lucas equation and linear fitting of DT‒time curve. The results showed that the DT sharply increases with increasing the NPs concentration while the SAR remains almost constant.

DOI: https://doi.org/10.1016/j.physc.2018.02.014

2.

Title: Effect of Interparticle Interactions on Hyperthermia Properties of Bare and Tri-ethylene glycol Coated Fe3O4 Nanoparticles

Abstract: Studies showed that interparticle dipole-dipole interactions strongly affect the hyperthermia output of a system of magnetic nanoparticles (NPs). In this paper we investigated the effect of dipole-dipole interactions on heat generation of a system of magnetic NPs by comparing the temperature rise and specific absorption rate (SAR) of two different samples. The first sample was a suspension of aggregated bare Fe3O4-NPs in distilled water and the second one was a suspension of Tri-ethylene glycol (TEG) coated Fe3O4. In order to investigate hyperthermia properties of the samples a high frequency AC magnetic field was applied to samples for 10 minutes. Results showed that heat generation of TEG coated sample is larger than the bare sample which corresponds with the fact that surface coating decrease interparticle interactions by increasing the interparticle distance.

Conference: 10th International conference on Magnetic and Superconducting Materials 2017

3.

Title: Effect of Alternating Magnetic Field and Size on Magnetic Hyperthermia Properties of Fe3O4 Nanoparticles Synthesized by Solvothermal Method

Abstract: In this work, we determined the effect of alternating magnetic field and size on magnetic hyperthermia properties of Fe3O4 nanoparticles. Fe3O4 nanoparticles of sizes 5, 10 and 18 nm were synthesized by using solvothermal method. The hydrodynamic diameter of these particles was measured with transmission electron microscope (TEM) and fitted with lognormal distribution function that showed their mono dispersity. The XRD pattern showed the spinel structure of prepared nanoparticles. The surface of nanoparticles was studied by FT-IR spectra. Magnetic hyperthermia property was investigated by homemade induction heater in high frequency alternating magnetic field with amplitude of 100, 300 and 700 Oe. The ∆T vs. time curves of different AC magnetic fields and sizes were recorded. Also the dependence of specific absorption rate on the AC magnetic field and size was investigated by analyzing the obtained ∆T vs. time curves.

Conference: 6th International Biennial Conference Ultra Fine Grained and Nanostructured Materials

Publisher: https://ufgnsm17.ut.ac.ir/paper?manu=29009

4.

Title: Magnetic Hyperthermia Properties of Biocompatible Iron Oxide Nanoparticles Coated with Oleic Acid and Poly-ethylene glycol with Different Concentrations

Abstract: Recent investigations showed that polymer coating reduces the amount of agglomeration. Hence iron oxide nanoparticles have been synthesized by co-precipitation method at 80 °C for 30 minutes and separately coated with two different surfactants which were oleic acid (OA) and poly-ethylen glycol (PEG). The structure and morphology of the nanoparticles were studied using XRD, TEM, and FTIR. In order to study the hyperthermia properties of coated samples, we prepared suspension of aggregated OA and PEG coated iron oxide nanoparticles in different concentrations, then we put them inside a cupper coil of a simple induction heater for approximately 15 minutes. The temperature rise (DT) of suspensions in the AC magnetic field were studied and the specific absorption rate (SAR) of samples were obtained from linear fitting of DT‒time curve. Results indicated that heat generation and SAR values of OA coated sample is larger than PEG coated one for the same concentration and also increasing the concentration leads to larger heat generation.

Conference: 6th International Biennial Conference Ultra Fine Grained and Nanostructured Materials

Publisher: https://ufgnsm17.ut.ac.ir/paper?manu=29021

Publications